A case-control study of elderly patients with acute respiratory illness: effect of influenza vaccination on admission to hospital in winter 2003-2004

Jordan, RE and Hawker, JI and Ayres, JG and Tunnicliffe, W and Adab, P and Olowokure, B and Kai, J and McManus, RJM and Salter, RA and Cheng, KK (2007) A case-control study of elderly patients with acute respiratory illness: effect of influenza vaccination on admission to hospital in winter 2003-2004. Vaccine, 25 (46). pp. 7909-13. ISSN 0264-410X

URL of Published Version: http://dx.doi.org/10.1016/j.vaccine.2007.09.005

Identification Number/DOI: 10.1016/j.vaccine.2007.09.005

Abstract

Every winter, hospitals face a large increase in emergency respiratory admissions in elderly people. A case-control study was undertaken to assess the effect of routine influenza vaccine in preventing such admissions among a cohort of UK elderly presenting with acute respiratory illness during winter 2003-2004. 157 hospitalised cases and 639 controls (matched for age, sex and week of consultation) were interviewed. In a winter typical of levels of circulating influenza in recent years, influenza vaccine did not show a protective effect on emergency respiratory admissions overall (adjusted OR 1.2 (95%CI 0.8, 1.9). Policy makers should not rely solely on influenza vaccine routinely having a large effect on winter pressures, and should focus on additional preventive strategies.

Type of Work:	Article
Contact e-mail:	r.e.jordan@bham.ac.uk and lt;r.e.jordan@bham.ac.uk and gt;
School/Faculty:	Schools (1998 to 2008) > School of Medicine
Department:	Epidemiology and Biostatistics, Public Health, Primary Care Clinical Sciences
Other Stated Affiliation:	Health Protection Research and Development Unit, Health Protection Agency, Department of Public Health and Epidemiology, University of Birmingham, Birmingham B15 2TT, United Kingdom. r.e.jordan@bham.ac.uk and lt;r.e.jordan@bham.ac.uk and gt;
Subjects:	R Medicine > RA Public aspects of medicine
ID Code:	66385

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